Polynucleotide Therapy, featuring the science-backed NCTF 135HA complex, is a next-generation injectable skin booster designed to repair tissue at the DNA level.
Polynucleotide Therapy is a non-surgical skin rejuvenation treatment that uses natural DNA fragments (polynucleotides) to repair damaged tissue, stimulate fibroblasts, and restore cellular function. The key formula we use – NCTF 135HA – delivers over 50 active ingredients, including amino acids, antioxidants, minerals, and hyaluronic acid.
Think of it as a skin “reset”: repairing fine lines, firming skin, and restoring hydration from the inside out. It’s ideal for:
This is an incredibly powerful anti-aging solution for all skin types and age groups.
Unlike traditional hyaluronic acid fillers, Polynucleotide Therapy doesn’t volumize. Instead, it strengthens your skin’s foundation by promoting DNA repair and collagen and elastin support.
You’ll notice:
This anti-aging injectable is especially popular among people looking for a subtle, refreshed appearance.
✅ Stimulates DNA-level repair for long-term skin rejuvenation
✅ Improves skin elasticity and firmness without adding volume
✅ Enhances hydration and glow in dry, dull, or aging skin
✅ Smooths fine lines and crepey texture, especially under the eyes
✅ Reduces under-eye darkness and puffiness safely and naturally
✅ Safe for sensitive areas and all skin types
✅ Supports collagen and elastin regeneration
Here’s the truth:
Most clinics don’t offer Polynucleotide Therapy (because few use evidence-based regenerative protocols).
At Therapeutic Aesthetics, we were among the first in the GTA to offer NCTF 135HA Polynucleotide Therapy with a focus on precision medicine and true skin regeneration.
Our approach isn’t cosmetic guesswork, it’s science-backed and clinically developed in partnership with the Canadian Association of Medical Aesthetics.
Avoiding intense heat or exercise for 24 hours
Skipping active skincare ingredients (like retinol or acids) for 3–5 days
Staying well-hydrated and using SPF daily
Booking your next session as part of a series of 3–5 treatments, spaced 3–4 weeks apart
During the Treatment:
Your provider will apply a numbing cream, then use microinjections to deliver NCTF 135HA into targeted areas. The procedure is precise and comfortable, usually lasting about 30 minutes.
Immediately After:
You may see mild redness or tiny bumps at the injection sites. These usually resolve within 24–48 hours.
Downtime:
There’s no required downtime. You can return to work or regular activity the same day, with some post-care recommendations provided.
Your journey to optimal aging starts with a conversation. Let our team of experts create a treatment plan tailored to your biology, lifestyle, and long-term wellness goals.
